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The game was officially announced by Capcom at their press conference during the 2010 Tokyo Game Show in September, confirming an earlier rumor in the May 2010 issue of Game Informer which said that the fifth Devil May Cry game would be developed by Ninja Theory. An announcement trailer was also released, giving players a taste of the new direction of the game. The title will use the Unreal Engine. In an interview published on the videogame blog Kotaku, lead producer Alex Jones explained that Capcom contacted Ninja Theory because of the good impression their previous game Heavenly Sword had on Capcom staff. Jones stated that Capcom executives appreciated the way Ninja Theory builds games around the characters and not vice-versa: in the interview he stated that "Outside of creating just amazing looking art, Ninja Theory really do embed narrative in their games in a way that is relatively sophisticated, Japanese game design also starts with a character and then builds a game out from there."
Initial reception to the new design of Dante and direction of the series was mostly negative.
In an interview, Capcom revealed that they knew Dante's new look would be met with negative backlash and that they pressed forward with this in mind: DmC is an origin story.