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Duke Nukem: Endangered Species was announced in January 2001. It was to be a hunting game where the player could hunt everything from dinosaurs to snakes, using an improved version of the engine used in the Carnivores series. The game was cancelled in December of that year. The company that had been developing the game, Ukraine-based Action Forms, went on to develop its own game, Vivisector: Beast Inside (originally titled Vivisector: Creatures of Doctor Moreau) instead.

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