Mass Effect 3
Flight Lieutenant Jeff "Joker" Moreau is a respected pilot with the Alliance Navy. Born and raised on Arcturus Station, he is widely considered to be the best helmsman in the Systems Alliance.
Moreau enlisted with the navy directly out of school and quickly gained the respect of his superiors. He served as pilot of both the Normandy SR-1 and its successor, the SR-2--and was at their respective helms during the Battle of the Citadel and the assault on the Collectors.
Moreau suffers from Vrolik syndrome, a rare, debilitating disorder also known as brittle bone disease.